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Summary of IV fluids composition (mmol/L)

Created: 26/10/2004
Updated: 17/5/2012
 


Fluid Na K Ca Cl Other pH

Crystalloids

Saline (0.9%) 154 - - 154 - 5.0
 Volulyte 137   4  0 110  Lactate 34
130,000 Daltons
Magnesium 1.5 mmol/L
Volume expansion 6 hours 
 6.0
Dextrose 4%/saline 0.18% 30 - - 30 Dextrose 40 g 4.0
Dextrose 5% - - - - Dextrose 50 g 4.0
Hartmann's 131 5 2 111 Lactate 29 6.5
Bicarbonate 8.4% 1000 - - - HCO3 1000 8
Colloids
 Gelatin 4% balanced
Isoplex
 145  4  0  105 30,000 Daltons 
Volume expansion 3-4 hours
7.4 
Haemaccel 145 5 6.25 145 Gelatin 35 g 7.4
Gelatin 4% Volplex or
Gelofusine
154 <0.4 <0.4 125 Gelatin 40 g 7.4
Hetastarch 154 - - 154 Starch 60 g 5.5
Pentastarch 154 - - 154 Starch 100 g 5.0
Albumin 4.5% <160 <2 - 136 Albumin 40-50 g 7.4

Table 1

Table 1 consists of products both balanced and unbalanced. Those with electrolyte levels similar to those found in plasma are considered balanced and therefore more unlikely to cause HCMA and risks associated with HCMA. For example, the gelatin Isoplex is a balanced intravenous fluid.

References



i] Volplex SPC, 2010
[1

iii] Wilkes N.  Anaesth Analg, 2001, 93, 811-816

iv] Lobo DN et al.  Crit Care Med 2010; Vol38, No 2.

v] Powell-Tuck et al.  (GIFTASUP)

vi] Reid F et al.  Clinical Sci 2003; 104: 17-24

vii] Stephens R et al. Trauma 2003; 5; 141
i] Volplex SPC, 2010

[2] Isoplex SPC, 2010

[3] Wilkes N et al. The effects of balanced versus saline-based hetastarch and crystalloid solutions on acid-base and electrolyte status and gastric mucosal perfusion in elderly surgical patients. Anaesth Analg 2001; 93: 811-816.

[4] Lobo DN et al. Effect of volume loading with 1 liter intravenous infusions of 0.9% saline, 4% succinylated gelatine (Gelofusine) and 6% hydroxyethyl starch (Voluven) on blood volume and endocrine responses: a randomized, three-way crossover study in healthy volunteers. Crit Care Med 2010; 38: 464-470.

[5] Powell-Tuck et al. Summary of The British Consensus Guidelines on Intravenous Fluid Therapy for Adult Surgical Patients (GIFTASUP).

[6] Reid F et al. (Ab)normal saline and physiological Hartmann's solution: a randomized double-blind crossover study. Clin Sci 2003; 104: 17-24

[7] Stephens R et al. Resuscitation fluids and hyperchloraemic metabolic acidosis. Trauma 2003; 5: 141-147.


ArticleDate:20041026
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