AnaesthesiaUK Journal

Morphine versus mexiletine for treatment of postamputation pain: a randomized, placebo-controlled, crossover trial

Thu, 14 Aug 2008 00:00:00 GMT

and phantom pains following amputations are often resistant to treatment. The authors investigated the efficacy of an opioid and a sodium channel blocker for post-amputation pain. Methods The authors conducted a double-blind, randomised, placebo-controlled, crossover study in adult patients with post-amputation pain of =6 months' duration and greater than 3 ......
Pain - Anesthesiology 2008; 109: 289-96
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Acupuncture and related techniques for postoperative pain: a systematic review of randomized controlled trials

Thu, 14 Aug 2008 00:00:00 GMT

authors carried out a systematic review to evaluate quantitatively the efficacy of acupuncture and related techniques as adjunct analgesics for acute postoperative pain management. Methods The authors searched the databases of Medline (1966-2007), CINAHL, The Cochrane Central Register of Controlled Trials (2006) and Scopus for randomised controlled trials (RCTs) using ......
Pain - Br J Anaesth 2008; 101: 151-60
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Contamination of salvaged maternal blood by amniotic fluid and fetal red cells during elective Caesarean section

Thu, 14 Aug 2008 00:00:00 GMT

Cell salvage in obstetrics is still controversial. The aim of this study was to measure amniotic fluid (AF), heparin and fetal red cell contamination of washed filtered salvaged maternal blood and to investigate differences based on the number of suction devices used. Methods Patients undergoing elective Caesarean section were ......
Obstetrics - Br J Anaesth 2008; 101: 225-9
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Epidural morphine injections for prevention of post dural puncture headache

Thu, 14 Aug 2008 00:00:00 GMT

The authors carried out a prospective, randomised, double-blind trial to study the effect of epidural morphine in the prevention of post-dural puncture headache in 25 parturients after inadvertent dural puncture. Methods Women were randomly allocated to receive two epidural injections, 24 hours apart, of either 3 mg morphine in ......
Obstetrics - Anaesthesia 2008; 63: 847-50
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Intensity of renal support in critically ill patients with acute kidney injury

Thu, 14 Aug 2008 00:00:00 GMT

The authors carried out a study to investigate the optimal intensity of renal-replacement therapy in critically ill patients with acute kidney injury. Methods The authors randomly assigned critically ill patients with acute kidney injury and failure of at least one non-renal organ or sepsis to receive intensive or less ......
Intensive Care - N Engl J Med 2008; 359: 7-20
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Vasopressin and epinephrine vs. epinephrine alone in cardiopulmonary resuscitation

Thu, 14 Aug 2008 00:00:00 GMT

A combination of vasopressin and epinephrine may be more effective than epinephrine or vasopressin alone during the administration of advanced cardiac life support for resuscitation from cardiac arrest, although there is insufficient evidence to make clinical recommendations. Methods The authors carried out a multicentre study, in which they randomly ......
Intensive Care - N Engl J Med 2008; 359: 21-30
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Does left molar approach to laryngoscopy make difficult intubation easier than the conventional midline approach?

Thu, 14 Aug 2008 00:00:00 GMT

Studies have found that the left molar approach of laryngoscopy can make difficult intubation easier. The present authors investigated whether this approach to laryngoscopy provided a better laryngeal view in cases of unexpected difficult intubation. orma Methods ormaOut of 1386 patients undergoing general anaesthesia for surgery, the authors recruited 20 ......
Anaesthesia - Eur J Anaesthesiol 2008; 25: 681-4
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Pleth variability index to monitor the respiratory variations in the pulse oximeter plethysmographic waveform amplitude and predict fluid responsiveness in the operating theatre

Thu, 14 Aug 2008 00:00:00 GMT

Respiratory variations in pulse oximetry plethysmographic waveform amplitude (DeltaPOP) can predict fluid responsiveness in mechanically ventilated patients but is difficult to assess at the bedside. Pleth variability index (PVI) is a new algorithm, which enables automated and continuous monitoring of DeltaPOP. These authors hypothesised that PVI can predict fluid ......
Anaesthesia - Br J Anaesth 2008; 101: 200-6
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Significance of the injection timing of ephedrine to reduce the onset time of rocuronium

Thu, 14 Aug 2008 00:00:00 GMT

The authors postulated that the onset time of rocuronium can be accelerated effectively if it is administered at the time when the effect of ephedrine on cardiac output has maximised. Methods A total of 75 male, anaesthetised, patients were randomly allocated to three groups: the "early" group (ephedrine 70? ......
Anaesthesia - Anaesthesia 2008; 63: 856-60
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Duration of sleep contributes to next-day pain report in the general population

Thu, 10 Jul 2008 00:00:00 GMT

Research suggests that the experiences of pain and sleep are bi-directionally connected. However, there have been no reports of whether sleep and pain experiences are prospectively linked to one another on a day-to-day basis in the general population. This study utilised data from a naturalistic, micro-longitudinal, telephone study using ......
Pain - Pain 2008; 137: 202-7
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