Potential therapies: Literature

The following are a selection of reviews of articles pertaining to the various metabolic and cytokine therapies that have been targeted at sepsis. A variety of these therapies appear in the 'Survivng Sepsis Guidelines'

Activated protein C Bernard et al. The PROWESS trial. NEJM 2001 Nadel et al. The RESOLVE trial. Lancet 2007 Vincent et al. The ENHANCE trial. CCM 2005 Abraham et al. The ADDRESS trial. NEJM 2005 Plasmapheresis Busund et al. Plasmapheresis RCT. ICM 2002 Steroids Bloomfield, Noble. Steroids for sepsis editorial. BJA 2004. Minneci et al. Meta-analysis. Ann Int Med 2004. Annane et al. Meta-analysis BMJ 2004 Immunoglobulins Turgeon et al. Intravenous immunoglobulin meta analysis. Ann Int Med 2007 Statins Kruger et al. Cohort analysis of statins and sepsis. ICM 2006