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Primary Viva 10 (Pharmacology)

Created: 7/9/2004

1) Pharmacokinetics

– Define “exponential”

– Why are the logarithms of concentrations plotted?

– Explain the information that can be obtained from a log concentration–time graph, including definitions.

– Define two-compartment model, zero and 1st order reactions, and non-linear kinetics.

2) Opioids

– What are their routes of administration?

– Describe the classification of opioid receptors.

– Draw the structure of morphine.

– Compare the characteristics of morphine, fentanyl, alfentanil and pethidine.

3) Regarding the treatment of diabetes

– What is the WHO/ADA classification?

– What do you know about the DCCT and UKPDS trials?

– Draw the structure of an insulin molecule.

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