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Turgeon et al. Intravenous immunoglobulin meta analysis. Ann Int Med 2007

Created: 21/5/2007
 

Paper type

Systematic Review and meta-analysis

Reference

Turgeon AF, Hutton B, Fergusson DA et al.
Meta-analysis: intravenous immunoglobulin in critically ill adult patients with sepsis.
Annals of Internal Medicine 2007; 146: 193-203

Major Finding

A survival benefit was observed for patients with sepsis who received polyclonal intravenous immunoglobulin therapy compared with those who received placebo or no intervention.

Point for discussion:

A large, randomized, controlled trial of polyclonal intravenous immunoglobulin therapy should be performed on the basis of the methodological limitations of the current literature. What is the potential benefit from this therapy in more severely ill patients? What is the potential effect of dosage and duration of this therapy?


ArticleDate:20070521
SiteSection: Article
 
   
    
                                            
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