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Vinsonneau et al. CVVH versus IHD in multi-organ failure. Lancet 2006

Created: 22/5/2007

Paper type

Randomised controlled trial


Vinsonneau C, Camus C, Combes A et al on behalf of the Hemodiafe Study Group. Continuous venovenous haemodiafiltration versus intermittent haemodialysis for acute renal failure in patients with multiple organ dysfunction syndrome: a multicentre randomised trial.
Lancet 2006; 368: 379-85.

Major Finding

Intermittent haemodialysis can be is as effective as CVVH in the treatment of patients with acute renal failure as part of multi organ dysfunction syndrome.

Point for discussion:

What doses of CVVH and IHD are optimal and should these doses not have been compared? Would the results have been the same if the patient characteristics were similiar between the CVVH and IHD groups?

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