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Merten et al. NaHCO3 and contrast nephropathy. JAMA 2004

Created: 22/5/2007
Updated: 22/5/2007

Paper type

Randomised controlled trial


Merten GJ,  Burgess WP, Gray LV et al.
Prevention of contrast-induced nephropathy with sodium bicarbonate: a randomized controlled trial.
JAMA 2004 291; (19):2328-34

Major Finding

Hydration with sodium bicarbonate before contrast exposure is more effective than hydration with sodium chloride for prophylaxis of contrast-induced renal nephropathy.

Point for discussion:

But should we prescribe sodium bicarbonate, n-acetyl cysteine or sodium bicarbonate AND n-acetyl cysteine?

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