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You are in Home >> Intensive Care >> Sepsis >> Infection >> Antibiotic Prescribing on the ICU


Created: 18/6/2007
Updated: 18/6/2007



Recommended First Line - Cefotaxime + Metronidazole

  • Upper tract source (e.g. perforated ulcer)  predominantly gram-positive infections
  • Lower tract (e.g. colon) predominantly anaerobic and gram-negative aerobes

Common pathogens                      Appropriate Antibiotics

Klebsiella species                                 Ceftazidime, Cipro, Imipenem

Enterobacter species                            3rd Gen Cefs, Cipro, Gent

Enterococcus                                       Penicillin + Gent

Anaerobes (secondary peritonitis)         Metronidazole, Clindamycin

Strep.pneumoniae                                Penicillin, 3rd Gen Cefs

Spontaneous Bacterial Peritonitis

3rd Gen Cefs, Cipro, Imipenem

CAPD (Tenchkof catheters)    

Vancomycin +/- antifungal

(consider yeasts and Staph aureus)

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