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Created: 23/4/2012
Updated: 15/5/2012
Isoplex, a 4% gelatin infusion, has a balanced electrolyte system reducing the risk of causing HCMA and associated issues. The levels of chloride in plasma are 98–107 mmol/L; within Isoplex they are 105 mmol/L. Isoplex has a half life of 3-4 hours, exerting its effect within the intravascular compartment. It has a low incidence of adverse reactions and there are no limitations on the volume that can be infused. When Isoplex needs to be given concomitantly with blood, it can be given through the same giving set due to negligible levels of calcium content. It can also be used to reconstitute packed red blood cells.

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