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Anti-NK1

Created: 5/4/2004
 



Anti-NK1 drugs are the subject of current research interest and may represent the final common pathway in the stimulation of the vomiting reflex. Blockade of the neurokinin-1 (NK1) receptor results in broad-spectrum anti-emesis in a range of species. The site of action is proposed to be in the brainstem. They have been shown to markedly reduce retching and vomiting. Whether they are effective in preventing nausea remains unclear.


ArticleDate:20040405
SiteSection: Article
 
   
    
                                            
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