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You are in Home >> Resources >> Clinical anaesthesia >> Nausea and vomiting

Combination therapy

Created: 5/4/2004

There is now great interest in using combinations of anti-emetics to increase efficacy. There are numerous studies indicating that combinations of different classes of antiemetics show clear improvements over monotherapy.


[i] Prospective randomized, double-blind comparative study of dexamethasone, ondansetron, and ondansetron plus dexamethasone as prophylactic antiemetic therapy in patients undergoing day-case gynaecological surgery.
Thomas R, Jones N.
Br J Anaesth 2001; 87(4): 588-92.

[ii] Prevention of vomiting after strabismus surgery in children: dexamethasone alone versus dexamethasone plus low-dose ondansetron.
Splinter WM.
Paediatr Anaesth 2001; 11(5): 591-5.

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