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The Primary ( ) and Final () FRCA examinations require an extensive knowledge of coagulation. We have therefore written a new educational resource section on the subject of coagulation, tests of coagulation, haemophilia and novel therapies in this area. The tutorials have been tailored to the FRCA syllabus and we have also added some past questions relevant to these topics.

Read other sections by using the navigation bar on the right side of every page. 

 Primary FRCA Syllabus

Physiology and Biochemistry

Red blood cells: haemoglobin and its variants. Blood groups….Haemostasis and coagulation…

Anaesthesia and resuscitation

 Management of massive haemorrhage, volume expansion, blood transfusion (hazards including incompatibility reaction)...  

Q. Primary OSCE Question

You are presented with a patient who has the following clotting results post-massive transfusion (INR 2.4, APTR 1.8, Platelets 45). Interpret these results and suggest a management plan.


 Final FRCA Syllabus

Applied Physiology

 Blood groups...alternative oxygen carrying solutions..abnormalities of coagulation and haemostasis..abnormal haemoglobins…sickle cell disease…thalassaemia…

Intensive Care Medicine

 Haematological disorders to include coagulopathies… 

Q. Short Answer Question

Discuss the management of massive transfusion

Q. Final Viva Question

Discuss your management of a patient with haemophilia scheduled for a total knee replacement on your list

Coagulation articles

Blood products
Transfusion reactions
Massive blood transfusion
Coagulation- classical model
A cell-based model of coagulation and the role of factor VIIa
Von Willebrand Disease
Recombinant Factor VII
Tests of coagulation
Major haemorrhage
Guidelines for autologous blood transfusion
Artificial blood
Guidelines for Jehovah’s Witnesses
Anticoagulants and the management of coagulopathy

Medical Animation (Blood Cells) from Ariva Bio Graphics on Vimeo.


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